Candida albicans Scavenges Host Zinc via Pra1 during Endothelial Invasion
Figure 2
In silico prediction of Pra1-zinc binding.
(A) Primary amino acid sequence of Pra1 (Candida Genome Database) with zinc-binding motifs in red. (B) Three-dimensional model of Pra1 built with Phyre2. (C) and (D) close-up of predicted zinc coordination sites. Note the presence of arginine, rather than glutamic acid at residue 179 (C) and that the C-terminal tail of Pra1 has multiple additional potential zinc binding histidine residues (D).