A High-Resolution View of Genome-Wide Pneumococcal Transformation
Figure 5
Distribution of secondary recombinations with respect to sequence divergence between the donor and recipient strains.
The red line represents the proportion of non-overlapping windows of the recipient sequence, containing at least one marker SNP, that have a mean SNP sequence identity of, or greater than, the threshold marked on the x axis. The blue line represents the same statistic for the subset of windows that overlap with at least one detected secondary RSS. The two lines are very similar, suggesting that recombinations are not concentrated in a subset of windows that have a relatively high level of sequence identity between the donor and recipient. A hypergeometric test for enrichment of recombinations in windows with high levels of sequence similarity was performed at 0.1% intervals; the calculated p values are displayed as a black dashed line relative to the y axis on the right side, confirming the lack of a significant relationship.