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Inflammation and Disintegration of Intestinal Villi in an Experimental Model for Vibrio parahaemolyticus-Induced Diarrhea

Figure 5

V. parahaemolyticus compromises epithelial barrier function in the small intestine.

Penetration of biotin (red) into the lamina propria in mock-infected (A) or V. parahaemolyticus-infected rabbits (B) at 25 hr PI. Tissues were counterstained with DAPI (blue) and phalloidin-Alexa 568 (yellow) to stain nucleic acid and F-actin, respectively. Note that biotin is located within the villi in sections from infected rabbits, but not in control rabbits. Adherent bacteria are marked with an arrowhead.

Figure 5

doi: https://doi.org/10.1371/journal.ppat.1002593.g005