Drosophila melanogaster as an Animal Model for the Study of Pseudomonas aeruginosa Biofilm Infections In Vivo
Figure 9
Kaplan-Meier survival curves of Drosophila orally infected (feeding) for 24h followed by subsequent acute (nicking) or secondary oral infection.
Survival following oral infection with (A) PAO1, (B) pelB::lux or (C) PAZH13 and relevant controls followed by acute infection with PAO1 or relevant controls. (D) Drosophila survival following oral infection with PAO1, pelB::lux, PAZH13 or uninfected (sucrose control) followed by oral infection with pelB::lux or uninfected (sucrose control). Strain name preceding the forward slash "/" indicates the strain or uninfected sucrose control used for oral infection of Drosophila; the strain name following the forward slash "/" indicates the strain or nicked (LB) or uninfected sucrose controls used for subsequent acute or secondary oral infection of Drosophila. Experiments were performed at least twice, each with a minimum of 100 flies and representative curves (mean +/- standard deviated) are shown. * p<0.05, ***p<0.001.