The Steroid Catabolic Pathway of the Intracellular Pathogen Rhodococcus equi Is Important for Pathogenesis and a Target for Vaccine Development
Figure 9
Histopathology of lung tissue of vaccinates versus non-vaccinated foals following intratracheal challenge with wild type R. equi.
Lung specimen of a vaccinated foal showing normal airways (bronchi and bronchioli), blood vessels and alveoli at (A) 25x and (B) 200x magnification. Typical pyogranuloma (5 mm diameter) observed in lung specimens of non-vaccinated control foals at (C) 25x and (D) 200x magnification. The centre of the pyogranuloma consists of necrotic debris, neutrophils and toxic neutrophils with complete loss of lung architecture.