The Trypanosoma cruzi Protease Cruzain Mediates Immune Evasion
Figure 7
Macrophage activation prevents T. cruzi intracellular development.
Mouse macrophages were infected with wild type T. cruzi and LPS was added as indicated. Mean parasites/cell were determined at 1 h and 48 h post-infection. Parasite death occurred when LPS was added prior to and concomitantly with T. cruzi trypomastigotes. Results are representative of two independent experiments (n = 3 per treatment).