Rotavirus Stimulates Release of Serotonin (5-HT) from Human Enterochromaffin Cells and Activates Brain Structures Involved in Nausea and Vomiting
Figure 3
NSP4 induces an increase in intracellular Ca2+ in human EC tumor cells.
GOT1 and primary EC t.c. were loaded with Fura-2 and Ca2+ measured before and after the addition of recombinant NSP4 (2 µM), for 40 min (GOT1 n = 8 cells, primary EC n = 10 cells). The asterisk (*) denotes statistical significance (P<0.01; Wilcoxon's rank sign test).