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The Binding of Triclosan to SmeT, the Repressor of the Multidrug Efflux Pump SmeDEF, Induces Antibiotic Resistance in Stenotrophomonas maltophilia

Figure 4

Effect of triclosan and quinolones alone or in combination on the growth of S. maltophilia.

Bacterial growth in presence of 3 µg/ml triclosan (solid brown lines) was slightly impaired compared with that in absence of the biocide (solid blue lines). However, in the presence of an antibiotic concentration that precluded bacterial growth this effect was reverted, and bacteria growing with triclosan and antibiotic (dotted brown lines) had an ameliorated growth compared to those growing in presence of the antibiotics but without the biocide (dotted blue lines).

Figure 4

doi: https://doi.org/10.1371/journal.ppat.1002103.g004