Transition of Plasmodium Sporozoites into Liver Stage-Like Forms Is Regulated by the RNA Binding Protein Pumilio
Figure 5
Ultrastructural evidence of puf2- parasites transforming into early liver stage EEFs in A. stephensi mosquito salivary glands.
Transmission electron microsocopy of 29-day salivary gland parasites showing the presence of slender-shaped, wild type and puf1- sporozoites with outer plasma membrane (PM) and entirely intact, inner membrane complex (IMC). puf2- salivary gland parasites developing into early EEFs show clear IMC disruption in the bulging region (arrows). Left pictures: longitudinal sections; right picture: transversal sections. Scale bars = 1 µm.