Completion of Hepatitis C Virus Replication Cycle in Heterokaryons Excludes Dominant Restrictions in Human Non-liver and Mouse Liver Cell Lines
Figure 5
Responsiveness of selected packaging cell lines to viral pathogen associated molecular patterns.
Given cell lines were inoculated with a recombinant La Crosse virus lacking the non-structural protein NSs (rLACVdelNSs;[32]). At 8 or 16 h post inoculation (p.i.) cells were collected and expression levels of IFN-β (left) and ISG56 (right) were determined by quantitative RT-PCR. The relative induction compared to cells that were not inoculated with the virus is given. Mean values of three independent experiments including the standard deviations are given.