Citrobacter rodentium is an Unstable Pathogen Showing Evidence of Significant Genomic Flux
Figure 7
PFGE of XbaI-digested C. rodentium genomic DNA from isolates recovered before and after mouse inoculation.
(A) PFGE profile of isolate ICC169-496 pre mouse inoculation (left) and isolate ICC169-496c10 recovered from mouse faeces 10 days post inoculation. (B) PFGE profile of isolate ICC169-407b15 recovered from mouse faeces 15 days post inoculation (left) compared to that of the infecting isolate ICC169-407 pre mouse inoculation (right). (C) PFGE profile of the pre mouse inoculation strain ICC180 compared to that for ICC180-P10 recovered from faeces after 10 passages though the mouse. Additional/missing bands are indicated by red arrows.