Selective C-Rel Activation via Malt1 Controls Anti-Fungal TH-17 Immunity by Dectin-1 and Dectin-2
Figure 5
Dectin-1 and dectin-2 contribute to Candida spp.-induced cytokine expression.
(A and B) Quantitative real-time PCR for indicated mRNAs in DCs stimulated with Candida albicans spp. (A), C. nivariensis or C. lusitaniae (B) in the absence or presence of blocking antibodies against dectin-1 and/or dectin-2. Expression is normalized to GAPDH and set at 1 in curdlan-stimulated cells. Data are mean ± s.d. of four independent experiments, *p<0.05 and **p<0.01 (Student's t-test).