Complement Receptor 1 Is a Sialic Acid-Independent Erythrocyte Receptor of Plasmodium falciparum
Figure 5
Representative examples of interaction between merozoites and CR1 on neuraminidase-treated and untreated control erythrocytes.
CR1 shows a characteristic speckled pattern with aggregation around the merozoite. All negative control antibodies showed no staining. CR1 and glycophorin A were stained with specific antibodies followed by fluorochrome-conjugated secondary antibodies against glycophorin (red) and CR1 (green). Merozoites (blue) were stained with the nucleic acid specific stain (Hoechst 33342). DIC = differential interference contrast.