Broadly Protective Monoclonal Antibodies against H3 Influenza Viruses following Sequential Immunization with Different Hemagglutinins
Figure 5
Anti-H3 mAbs protect against H3 virus in vivo.
Mice were given 30mg/kg mAb 7A7, 12D1, 39A4 or isotype control by intraperitoneal injection 1 hour prior, 24 hours post (12D1 only) or 48 hours post (12D1 only) challenge with H3N2 reassortant virus (HK68/PR8). N = 5 per group.