Trypanosome Lytic Factor, an Antimicrobial High-Density Lipoprotein, Ameliorates Leishmania Infection
Figure 5
L. amazonensis promastigotes but not amastigotes are sensitive to lytic HDL within macrophages.
BALB/c bone-marrow derived macrophages were infected with L. amazonensis promastigotes (A) or amastigote like forms (B) at a multiplicity of infection of 3∶1, for 2 hours before the addition of human or bovine HDL (1.5 mg/ml) for 24 hours. The data represent the mean±SD of duplicate cultures of one typical experiment that has been repeated twice. *** p<0.0001 compared to bovine HDL, ANOVA test.