Stimulation of Chitin Synthesis Rescues Candida albicans from Echinocandins
Figure 5
Cells pre-grown in glucosamine have reduced susceptibility to caspofungin.
Pre-growing strains that were hypersensitive to caspofungin (chs3Δ, cna1Δ, mkc1Δ) in YPD plus 23 mM glucosamine reduced their susceptibility to 0.032 µg/ml caspofungin. Cell numbers per spot are from 5000, 500, 50 to 5 cells, from left to right.