Release of Hepatic Plasmodium yoelii Merozoites into the Pulmonary Microvasculature
Figure 5
Dynamics of Merosome Transport in the Liver
(A) Multiple merosomes separate from an EEF and are rapidly transported towards the central vein (see Video S6). Bar = 10μm.
(B) Large merosomes move slowly within the sinusoidal lumen (see Video S7). Remnant bodies can be differentiated from merozoites by their larger size and lack of GFP (arrows). Bar = 10 μm.
(C–G) Individual frames of an intravital confocal video showing two smaller merosomes gliding along a sinusoid. Bars = 10 μm.
(H) Semithin liver section 52 h after infection with P. yoelii. Multiple merosomes, presumably released from a single EEF, can be found inside the sinusoids (arrows). Note the presence of remnant bodies in merosomes. Bar = 10 μm.