Bordetella pertussis, the Causative Agent of Whooping Cough, Evolved from a Distinct, Human-Associated Lineage of B. bronchiseptica
Figure 5
Model of the Evolution of the Mammalian Bordetellae
The bar on the left indicates increasing degrees of adaptation to the human host. Arrows indicate descent; double arrows between complexes indicate possible within-host immune competition. In boxes, genetic events are shown that may have played a role in speciation and niche adaptation. Numbers between parentheses refer to references. See text for details.