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The Cell Cycle Independence of HIV Infections Is Not Determined by Known Karyophilic Viral Elements

Figure 5

IN Does Not Determine the Infectivity in Non-Dividing Cells

Aphidicolin-treated HeLa cells were infected with increasing amount of luciferase-encoding viruses described in Figure 1. Culture supernatants of transfected cells were used as the inoculum. Virus infectivity was judged by measuring luciferase titers of infected cell lysates 2 d after infection. RLU; relative light units. White circles indicate cells without aphidicolin. Filled circles indicate cells with aphidicolin (2 μg per ml). This is a representative experiment that was done at least three times for each virus.

Figure 5

doi: https://doi.org/10.1371/journal.ppat.0010018.g005