Tac1 deficiency reduces the severity of enteric bacterial infection

Elliot Lloyd; Michael Cremin; Emmy Tay; Kristina Sanchez; Jungjae Park; YuanYuan Lei; Melanie G. Gareau; Colin Reardon

doi:10.1371/journal.ppat.1014587

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Open Access

Peer-reviewed

Research Article

Tac1 deficiency reduces the severity of enteric bacterial infection

Elliot Lloyd ,

Contributed equally to this work with: Elliot Lloyd, Michael Cremin

Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

Affiliation Department of Anatomy, Physiology & Cell Biology. School of Veterinary Medicine, University of California Davis, Davis, California. United States of America
⨯
Michael Cremin ,

Contributed equally to this work with: Elliot Lloyd, Michael Cremin

Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Department of Anatomy, Physiology & Cell Biology. School of Veterinary Medicine, University of California Davis, Davis, California. United States of America
⨯
Emmy Tay,

Roles Formal analysis, Investigation, Writing – review & editing

Affiliation Department of Anatomy, Physiology & Cell Biology. School of Veterinary Medicine, University of California Davis, Davis, California. United States of America
⨯
Kristina Sanchez,

Roles Investigation

Affiliation Department of Anatomy, Physiology & Cell Biology. School of Veterinary Medicine, University of California Davis, Davis, California. United States of America
⨯
Jungjae Park,

Roles Investigation

Affiliation Department of Anatomy, Physiology & Cell Biology. School of Veterinary Medicine, University of California Davis, Davis, California. United States of America
⨯
YuanYuan Lei,

Roles Investigation

Affiliation Department of Anatomy, Physiology & Cell Biology. School of Veterinary Medicine, University of California Davis, Davis, California. United States of America
⨯
Melanie G. Gareau,

Roles Conceptualization, Writing – review & editing

Affiliation Department of Anatomy, Physiology & Cell Biology. School of Veterinary Medicine, University of California Davis, Davis, California. United States of America
⨯
Colin Reardon

Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

* E-mail: creardon@ucdavis.edu

Affiliation Department of Anatomy, Physiology & Cell Biology. School of Veterinary Medicine, University of California Davis, Davis, California. United States of America

https://orcid.org/0000-0003-2204-8091

⨯

Tac1 deficiency reduces the severity of enteric bacterial infection

Elliot Lloyd,
Michael Cremin,
Emmy Tay,
Kristina Sanchez,
Jungjae Park,
YuanYuan Lei,
Melanie G. Gareau,
Colin Reardon

Published: September 18, 2026
https://doi.org/10.1371/journal.ppat.1014587

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