The TRAF6-Akt axis is required for efficient lytic replication of KSHV

• Zhenshan Liu ,

  Roles Funding acquisition, Investigation, Methodology, Validation, Visualization, Writing – original draft

  ¶‡ These authors contributed equally to this work.

  Affiliations Institute of Pediatric Infection, Immunity, and Critical Care Medicine, Shanghai Children’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Shanghai Institute of Immunology, Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China

  ⨯
• Qingyu Guo ,

  Roles Investigation, Methodology, Validation

  ¶‡ These authors contributed equally to this work.

  Affiliations Institute of Pediatric Infection, Immunity, and Critical Care Medicine, Shanghai Children’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Shanghai Institute of Immunology, Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China

  ⨯
• Weili Wang,

  Roles Investigation, Methodology

  Affiliation Institute of Pediatric Infection, Immunity, and Critical Care Medicine, Shanghai Children’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

  ⨯
• Hongjia Lu,

  Roles Investigation, Methodology

  Affiliations Institute of Pediatric Infection, Immunity, and Critical Care Medicine, Shanghai Children’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Shanghai Institute of Immunology, Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China

  ⨯
• Tianyu Yu ,

  Roles Investigation, Methodology

  * E-mail: yutianyu@jlu.edu.cn (TY); tingtingli339@hunnu.edu.cn (TL); liangqiming@shsmu.edu.cn (QL)

  Affiliation Department of Thyroid Surgery, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China

  ⨯
• Tingting Li ,

  Roles Funding acquisition, Investigation

  * E-mail: yutianyu@jlu.edu.cn (TY); tingtingli339@hunnu.edu.cn (TL); liangqiming@shsmu.edu.cn (QL)

  Affiliation State Key Laboratory of Developmental Biology of Freshwater Fish, Human International Joint Laboratory of Animal Intestinal Ecology and Health, Laboratory of Animal Nutrition and Human Health, Hunan Provincial Key Laboratory of Animal Intestinal Function and Regulation, College of Life Sciences, Hunan Normal University, Changsha, Hunan, China

  ⨯
• Qiming Liang

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  * E-mail: yutianyu@jlu.edu.cn (TY); tingtingli339@hunnu.edu.cn (TL); liangqiming@shsmu.edu.cn (QL)

  Affiliations Institute of Pediatric Infection, Immunity, and Critical Care Medicine, Shanghai Children’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Shanghai Institute of Immunology, Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Shanghai Key Laboratory of Severe Respiratory Infection, Shanghai, China

  https://orcid.org/0000-0003-4792-1547

  ⨯