Viral Nuclease Inhibitors: Small molecule disruptors of the UL12 alkaline nuclease display broad anti-herpes virus activity

• Nidhi Sharma,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Molecular Biology and Biophysics, University of Connecticut School of Medicine, Farmington, Connecticut, United States of America

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• Xiaoyun Xie,

  Roles Data curation, Investigation, Methodology, Resources, Validation, Writing – review & editing

  Affiliation Department of Pharmaceutical Sciences, University of Connecticut School of Pharmacy, Storrs, Connecticut, United States of America

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• Renata Szczepaniak,

  Roles Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Department of Molecular Biology and Biophysics, University of Connecticut School of Medicine, Farmington, Connecticut, United States of America

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• Chitra Rani,

  Roles Investigation, Validation, Writing – review & editing

  Affiliation Department of Molecular Biology and Biophysics, University of Connecticut School of Medicine, Farmington, Connecticut, United States of America

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• Sheida Khojasteh Khosro,

  Roles Investigation, Resources, Validation, Writing – review & editing

  Affiliation Department of Chemistry, University of Connecticut School of Pharmacy, Storrs, Connecticut, United States of America

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• Jolanta Krucinska,

  Roles Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Department of Pharmaceutical Sciences, University of Connecticut School of Pharmacy, Storrs, Connecticut, United States of America

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• Xiaoling Chen,

  Roles Investigation, Resources, Validation

  Affiliation Department of Pharmaceutical Sciences, University of Connecticut School of Pharmacy, Storrs, Connecticut, United States of America

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• Dung Do,

  Roles Investigation, Resources, Validation

  Affiliation Department of Pharmaceutical Sciences, University of Connecticut School of Pharmacy, Storrs, Connecticut, United States of America

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• Lee Wright,

  Roles Conceptualization, Formal analysis, Investigation, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmaceutical Sciences, University of Connecticut School of Pharmacy, Storrs, Connecticut, United States of America

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• Dennis Wright ,

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: dennis.wright@uconn.edu (DW), weller@uchc.edu (SW)

  Affiliation Department of Pharmaceutical Sciences, University of Connecticut School of Pharmacy, Storrs, Connecticut, United States of America

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• Sandra Weller

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: dennis.wright@uconn.edu (DW), weller@uchc.edu (SW)

  Affiliation Department of Molecular Biology and Biophysics, University of Connecticut School of Medicine, Farmington, Connecticut, United States of America

  https://orcid.org/0000-0002-4519-6276

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