Loss of type I interferon signaling in Kupffer cells triggers viral spread and fatal liver damage in a mouse model of Crimean-Congo hemorrhagic fever

• Shintaro Yamada ,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft

  ¶¤ Current address: Department of Pathology, The University of Texas Medical Branch at Galveston, Galveston, Texas, United States of America.

  Affiliation Institute of Cardiovascular Immunology, University Hospital Bonn, University of Bonn, Bonn, Germany

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• Masayuki Shimojima,

  Roles Resources, Writing – review & editing

  Affiliation Department of Virology I, National Institute of Infectious Diseases, Japan Institute for Health Security, Musashimurayama, Tokyo, Japan

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• Takeshi Saito,

  Roles Data curation, Investigation, Resources, Writing – review & editing

  Affiliation Department of Pathology, The University of Texas Medical Branch at Galveston, Galveston, Texas, United States of America

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• Junki Maruyama ,

  Roles Data curation, Funding acquisition, Investigation, Methodology, Resources, Validation, Writing – review & editing

  * E-mail: jumaruya@utmb.edu (JM); hkato@uni-bonn.de (HK)

  Affiliations Department of Pathology, The University of Texas Medical Branch at Galveston, Galveston, Texas, United States of America, Institute for Human Infections and Immunity, The University of Texas Medical Branch at Galveston, Galveston, Texas, United States of America

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• Hiroki Kato

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

  * E-mail: jumaruya@utmb.edu (JM); hkato@uni-bonn.de (HK)

  Affiliation Institute of Cardiovascular Immunology, University Hospital Bonn, University of Bonn, Bonn, Germany

  https://orcid.org/0000-0002-9571-4895

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