Single amino acid substitution in RdRp reduces viral recombination frequency of NADC30-like porcine reproductive and respiratory syndrome virus type 2

• Xingyang Cui ,

  Contributed equally to this work with: Xingyang Cui, Hao Song, Xinyi Huang, Dasong Xia

  Roles Conceptualization, Investigation, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations State Key Laboratory of Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China, College of Animal Science, Wenzhou Vocational College of Science and Technology, Wenzhou, China

  ⨯
• Hao Song ,

  Contributed equally to this work with: Xingyang Cui, Hao Song, Xinyi Huang, Dasong Xia

  Roles Investigation, Validation, Visualization, Writing – review & editing

  Affiliation State Key Laboratory of Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Xinyi Huang ,

  Contributed equally to this work with: Xingyang Cui, Hao Song, Xinyi Huang, Dasong Xia

  Roles Funding acquisition, Validation, Writing – review & editing

  Affiliation State Key Laboratory of Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Dasong Xia ,

  Contributed equally to this work with: Xingyang Cui, Hao Song, Xinyi Huang, Dasong Xia

  Roles Validation, Visualization

  Affiliation State Key Laboratory of Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Yongbo Yang,

  Roles Investigation

  Affiliation State Key Laboratory of Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Xiaoxiao Tian,

  Roles Investigation

  Affiliation State Key Laboratory of Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Tao Wang,

  Roles Validation

  Affiliation State Key Laboratory of Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Guoqing Liu,

  Roles Investigation

  Affiliation State Key Laboratory of Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Zameel Saleem,

  Roles Validation

  Affiliation State Key Laboratory of Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Haiwei Wang ,

  Roles Conceptualization, Writing – original draft, Writing – review & editing

  * E-mail: antongqing@caas.cn (TA); wanghaiwei@caas.cn (HW)

  Affiliation State Key Laboratory of Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China

  ⨯
• Tongqing An

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: antongqing@caas.cn (TA); wanghaiwei@caas.cn (HW)

  Affiliations State Key Laboratory of Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China, Heilongjiang Provincial Key Laboratory of Veterinary Immunology, Harbin, China

  https://orcid.org/0000-0003-4619-4587

  ⨯