The SARS-CoV-2 S2′-helix compared to stem helix confers higher genetic barrier to antibody resistance

• Xuanjia Wang,

  Roles Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliation Shanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai, China

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• Shitong Qiao,

  Roles Investigation, Methodology

  Affiliation Center for Infection Biology, School of Basic Medical Sciences, Tsinghua University, Beijing, China

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• Zhiheng Bao,

  Roles Investigation

  Affiliation Shanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai, China

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• Jiaxiu Bai,

  Roles Investigation

  Affiliation Shanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai, China

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• Chunyan Yi,

  Roles Funding acquisition, Methodology, Resources

  Affiliation Key Laboratory of Multi-Cell Systems, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China

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• Qiang Ding,

  Roles Supervision, Funding acquisition, Resources, Methodology

  Affiliation Center for Infection Biology, School of Basic Medical Sciences, Tsinghua University, Beijing, China

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• Xiaoyu Sun

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: sunxiaoyu@fudan.edu.cn

  Affiliation Shanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai, China

  https://orcid.org/0009-0000-1265-4544

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