Targeted lysosomal activation in bladder epithelium enhances clearance of intracellular uropathogenic Escherichia coli

• Kathrin Tomasek ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: kathrin.tomasek@epfl.ch

  Affiliation Laboratory of Microbiology and Microtechnology, School of Life Sciences (SV), École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

  https://orcid.org/0000-0003-3768-877X

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• Kristina Skurvydaite,

  Roles Data curation, Formal analysis, Investigation, Writing – review & editing

  Current address: Department of Genetic Medicine and Development (CMU), Faculty of Medicine, 1211 Geneva, Switzerland

  Affiliation Laboratory of Microbiology and Microtechnology, School of Life Sciences (SV), École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

  https://orcid.org/0009-0009-6110-0885

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• Gauri Paduthol ,

  Roles Data curation, Formal analysis, Investigation, Writing – review & editing

  ¶‡ These authors are joint senior authors on this work. GP, AMB, LS and VB also contributed equally to this work.

  Affiliation Laboratory of Microbiology and Microtechnology, School of Life Sciences (SV), École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

  https://orcid.org/0000-0002-6654-3281

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• Allison M. Burns ,

  Roles Data curation, Formal analysis, Investigation, Visualization, Writing – review & editing

  ¶‡ These authors are joint senior authors on this work. GP, AMB, LS and VB also contributed equally to this work.

  Affiliation Bioinformatics Competence Centre, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

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• Léa Schlunke ,

  Roles Data curation, Investigation

  ¶‡ These authors are joint senior authors on this work. GP, AMB, LS and VB also contributed equally to this work.

  Affiliation Laboratory of Microbiology and Microtechnology, School of Life Sciences (SV), École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

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• Valentin Borgeat ,

  Roles Data curation, Formal analysis, Investigation, Writing – review & editing

  ¶‡ These authors are joint senior authors on this work. GP, AMB, LS and VB also contributed equally to this work.

  Affiliation Laboratory of Microbiology and Microtechnology, School of Life Sciences (SV), École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

  https://orcid.org/0000-0003-2933-2458

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• Christian Pasquali ,

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – review & editing

  ¶‡ These authors are joint senior authors on this work. GP, AMB, LS and VB also contributed equally to this work.

  Affiliation OM Pharma Ltd., Meyrin/Geneva, Switzerland

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• Mario Romani ,

  Roles Conceptualization, Methodology, Project administration, Supervision, Visualization, Writing – review & editing

  ¶‡ These authors are joint senior authors on this work. GP, AMB, LS and VB also contributed equally to this work.

  Affiliation OM Pharma Ltd., Meyrin/Geneva, Switzerland

  https://orcid.org/0000-0001-9292-8807

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• John D. McKinney

  Roles Conceptualization, Funding acquisition, Resources, Supervision

  ¶‡ These authors are joint senior authors on this work. GP, AMB, LS and VB also contributed equally to this work.

  Affiliation Laboratory of Microbiology and Microtechnology, School of Life Sciences (SV), École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

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