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Open Access
Peer-reviewed
Research Article
Potential threats of porcine Getah virus outbreaks and its specific antagonism of host antiviral response through proteasome-dependent degradation of P46 by nsP2
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Yang Wu ,
Contributed equally to this work with: Yang Wu, He Zhang, Mingwei Li, Shanshan Song, Qian Yang
Roles Conceptualization, Data curation, Investigation, Project administration, Writing – original draft
Affiliation State Key Laboratory of Animal Disease Control and Prevention, Chinese Academy of Agricultural Sciences Harbin Veterinary Research Institute, Harbin, China
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He Zhang ,
Contributed equally to this work with: Yang Wu, He Zhang, Mingwei Li, Shanshan Song, Qian Yang
Roles Resources, Software, Validation
Affiliation State Key Laboratory of Animal Disease Control and Prevention, Chinese Academy of Agricultural Sciences Harbin Veterinary Research Institute, Harbin, China
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Mingwei Li ,
Contributed equally to this work with: Yang Wu, He Zhang, Mingwei Li, Shanshan Song, Qian Yang
Roles Conceptualization, Writing – original draft, Writing – review & editing
Affiliation State Key Laboratory of Animal Disease Control and Prevention, Chinese Academy of Agricultural Sciences Harbin Veterinary Research Institute, Harbin, China
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Shanshan Song ,
Contributed equally to this work with: Yang Wu, He Zhang, Mingwei Li, Shanshan Song, Qian Yang
Roles Project administration, Writing – original draft
Affiliations Exotic Herbivore Diseases Surveillance and Research Center, China Animal Health and Epidemiology Center, Qingdao, China, Molecular biology, YEBIO Bio- Engineering Co., Ltd. of Qingdao, Qingdao, China
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Qian Yang ,
Contributed equally to this work with: Yang Wu, He Zhang, Mingwei Li, Shanshan Song, Qian Yang
Roles Resources, Validation, Writing – original draft, Writing – review & editing
Affiliation Laboratory of Medical Genetics, Harbin Medical University, Harbin, China
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Yaqin Dong,
Roles Investigation, Methodology, Writing – review & editing
Affiliation Exotic Herbivore Diseases Surveillance and Research Center, China Animal Health and Epidemiology Center, Qingdao, China
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Yongrui Wang,
Roles Data curation, Formal analysis, Writing – original draft
Affiliation State Key Laboratory of Animal Disease Control and Prevention, Chinese Academy of Agricultural Sciences Harbin Veterinary Research Institute, Harbin, China
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Xuepeng Wang,
Roles Investigation, Software, Writing – original draft
Affiliation State Key Laboratory of Animal Disease Control and Prevention, Chinese Academy of Agricultural Sciences Harbin Veterinary Research Institute, Harbin, China
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Ju Zhang,
Roles Data curation, Methodology, Validation
Affiliation State Key Laboratory of Animal Disease Control and Prevention, Chinese Academy of Agricultural Sciences Harbin Veterinary Research Institute, Harbin, China
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Jin Tian ,
Roles Project administration, Supervision, Writing – review & editing
* E-mail: fengli@caas.cn (LF), guolongjun@caas.cn (LG), zhangfeng@cahec.cn (FZ), tj6049345@126.com (JT)
Affiliation State Key Laboratory of Animal Disease Control and Prevention, Chinese Academy of Agricultural Sciences Harbin Veterinary Research Institute, Harbin, China
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Feng Zhang ,
Roles Project administration, Writing – original draft, Writing – review & editing
* E-mail: fengli@caas.cn (LF), guolongjun@caas.cn (LG), zhangfeng@cahec.cn (FZ), tj6049345@126.com (JT)
Affiliation Exotic Herbivore Diseases Surveillance and Research Center, China Animal Health and Epidemiology Center, Qingdao, China
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Longjun Guo ,
Roles Conceptualization, Resources, Writing – original draft, Writing – review & editing
* E-mail: fengli@caas.cn (LF), guolongjun@caas.cn (LG), zhangfeng@cahec.cn (FZ), tj6049345@126.com (JT)
Affiliation State Key Laboratory of Animal Disease Control and Prevention, Chinese Academy of Agricultural Sciences Harbin Veterinary Research Institute, Harbin, China
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Li Feng
Roles Project administration, Supervision, Writing – review & editing
* E-mail: fengli@caas.cn (LF), guolongjun@caas.cn (LG), zhangfeng@cahec.cn (FZ), tj6049345@126.com (JT)
Affiliation State Key Laboratory of Animal Disease Control and Prevention, Chinese Academy of Agricultural Sciences Harbin Veterinary Research Institute, Harbin, China
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Potential threats of porcine Getah virus outbreaks and its specific antagonism of host antiviral response through proteasome-dependent degradation of P46 by nsP2
- Yang Wu,
- He Zhang,
- Mingwei Li,
- Shanshan Song,
- Qian Yang,
- Yaqin Dong,
- Yongrui Wang,
- Xuepeng Wang,
- Ju Zhang,
- Jin Tian
- Published: August 26, 2026
- https://doi.org/10.1371/journal.ppat.1014447