Novel duck reovirus σC hijacks the mitochondrial COQ6–CoQ10 axis to drive NLRP3-dependent pyroptosis

• Hui Yan ,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources

  ¶‡ These authors contributed equally to this work.

  Affiliations Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Tai’an, China, Shandong Provincial Key Laboratory of Zoonoses, Shandong Agricultural University, Tai’an, China

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• Lei Bei ,

  Roles Investigation, Resources, Validation

  ¶‡ These authors contributed equally to this work.

  Affiliations Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Tai’an, China, Shandong Provincial Key Laboratory of Zoonoses, Shandong Agricultural University, Tai’an, China

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• Mingrui Zhao,

  Roles Investigation, Validation

  Affiliations Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Tai’an, China, Shandong Provincial Key Laboratory of Zoonoses, Shandong Agricultural University, Tai’an, China

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• Jiajun Wang,

  Roles Visualization

  Affiliations Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Tai’an, China, Shandong Provincial Key Laboratory of Zoonoses, Shandong Agricultural University, Tai’an, China

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• Pengxiang Jin,

  Roles Resources

  Affiliations Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Tai’an, China, Shandong Provincial Key Laboratory of Zoonoses, Shandong Agricultural University, Tai’an, China

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• Chunmei Xu,

  Roles Investigation

  Affiliations Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Tai’an, China, Shandong Provincial Key Laboratory of Zoonoses, Shandong Agricultural University, Tai’an, China

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• Lin Ju,

  Roles Visualization

  Affiliations Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Tai’an, China, Shandong Provincial Key Laboratory of Zoonoses, Shandong Agricultural University, Tai’an, China

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• Yu Meng,

  Roles Project administration

  Affiliations Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Tai’an, China, Shandong Provincial Key Laboratory of Zoonoses, Shandong Agricultural University, Tai’an, China

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• Shijin Jiang,

  Roles Funding acquisition, Project administration, Supervision

  Affiliations Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Tai’an, China, Shandong Provincial Key Laboratory of Zoonoses, Shandong Agricultural University, Tai’an, China

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• Ruihua Zhang

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: rhzhang@sdau.edu.cn

  Affiliations Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Tai’an, China, Shandong Provincial Key Laboratory of Zoonoses, Shandong Agricultural University, Tai’an, China

  https://orcid.org/0000-0002-7778-1509

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