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Structural basis of a conserved, broad antigenic region surrounding the five-fold axis of foot-and-mouth disease virus revealed by swine neutralizing antibodies
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Qiongqiong Zhao ,
Contributed equally to this work with: Qiongqiong Zhao, Shanquan Wu, Fengjuan Li
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft
Affiliations State Key Laboratory of Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China, National Key Laboratory of Agricultural Microbiology, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan, China, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China
⨯ - Shanquan Wu ,
- Fengjuan Li ,
- Lv Lv,
- Shulun Huang,
- Jiaxin Yang,
- Zhanhui Zhu,
- Ying Sun,
- Pinghua Li,
- Yimei Cao,
- Huifang Bao,
- Pu Sun,
- Xingwen Bai,
- Zhixun Zhao,
- Jing Zhang,
- Jinyan Wu,
- Hong Yuan,
- Jijun He,
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Xiangmin Li ,
Roles Conceptualization, Data curation, Formal analysis, Methodology, Project administration, Resources, Supervision, Writing – review & editing
* E-mail: lixiangmin@mail.hzau.edu.cn (XL); luzengjun@caas.cn (ZL); leids@lzu.edu.cn (DL); likun02@caas.cn (KL)
Affiliations National Key Laboratory of Agricultural Microbiology, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan, China, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China, Hubei Jiangxia Laboratory, Wuhan, China
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Zengjun Lu ,
Roles Conceptualization, Formal analysis, Methodology, Project administration, Resources, Supervision, Writing – review & editing
* E-mail: lixiangmin@mail.hzau.edu.cn (XL); luzengjun@caas.cn (ZL); leids@lzu.edu.cn (DL); likun02@caas.cn (KL)
Affiliations State Key Laboratory of Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China, Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou, China
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Dongsheng Lei ,
Roles Conceptualization, Formal analysis, Funding acquisition, Software, Writing – original draft, Writing – review & editing
* E-mail: lixiangmin@mail.hzau.edu.cn (XL); luzengjun@caas.cn (ZL); leids@lzu.edu.cn (DL); likun02@caas.cn (KL)
Affiliations State Key Laboratory of Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China, School of Physical Science and Technology, Electron Microscopy Centre of Lanzhou University, Lanzhou University, Lanzhou, China, Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, China
⨯ - [ ... ],
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Kun Li
Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: lixiangmin@mail.hzau.edu.cn (XL); luzengjun@caas.cn (ZL); leids@lzu.edu.cn (DL); likun02@caas.cn (KL)
Affiliations State Key Laboratory of Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China, Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou, China
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https://orcid.org/0009-0006-4934-4738
Structural basis of a conserved, broad antigenic region surrounding the five-fold axis of foot-and-mouth disease virus revealed by swine neutralizing antibodies
- Qiongqiong Zhao,
- Shanquan Wu,
- Fengjuan Li,
- Lv Lv,
- Shulun Huang,
- Jiaxin Yang,
- Zhanhui Zhu,
- Ying Sun,
- Pinghua Li,
- Yimei Cao
- Published: July 14, 2026
- https://doi.org/10.1371/journal.ppat.1014357