Japanese encephalitis virus hijacks the host purine biosynthetic network to promote viral replication in neurons

• Jun Gu,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliations National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China, Hubei Hongshan Laboratory, Wuhan, Hubei, China, Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China, Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China

  ⨯
• Chencheng Fan,

  Roles Formal analysis, Investigation, Software, Validation, Visualization

  Affiliations National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China, Hubei Hongshan Laboratory, Wuhan, Hubei, China, Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China, Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China

  ⨯
• Shengxian Xiang,

  Roles Investigation, Validation

  Affiliations National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China, Hubei Hongshan Laboratory, Wuhan, Hubei, China, Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China, Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China

  ⨯
• Ling’en Yang,

  Roles Investigation, Software

  Affiliation Key Laboratory of Animal Pathogen Infection and Immunology of Fujian Province, College of Animal Sciences, Fujian Agriculture and Forestry University, Fuzhou, China

  ⨯
• Jia Liu,

  Roles Investigation

  Affiliations National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China, Hubei Hongshan Laboratory, Wuhan, Hubei, China, Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China, Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China

  ⨯
• Youhui Si,

  Roles Resources, Supervision

  Affiliations National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China, Hubei Hongshan Laboratory, Wuhan, Hubei, China, Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China, Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China

  ⨯
• Bibo Zhu,

  Roles Resources, Supervision

  Affiliations National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China, Hubei Hongshan Laboratory, Wuhan, Hubei, China, Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China, Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China

  ⨯
• Yingjie Sun,

  Roles Resources, Supervision

  Affiliation Department of Avian Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Science, Shanghai, China

  ⨯
• Chan Ding ,

  Roles Conceptualization, Resources, Supervision, Writing – review & editing

  * E-mail: yej@mail.hzau.edu.cn (YJ); sbcao@mail.hzau.edu.cn (SC); shoveldeen@shvri.ac.cn (CD)

  Affiliations Department of Avian Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Science, Shanghai, China, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China

  ⨯
• Shengbo Cao ,

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – original draft

  * E-mail: yej@mail.hzau.edu.cn (YJ); sbcao@mail.hzau.edu.cn (SC); shoveldeen@shvri.ac.cn (CD)

  Affiliations National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China, Hubei Hongshan Laboratory, Wuhan, Hubei, China, Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China, Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China

  ⨯
• Jing Ye

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: yej@mail.hzau.edu.cn (YJ); sbcao@mail.hzau.edu.cn (SC); shoveldeen@shvri.ac.cn (CD)

  Affiliations National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China, Hubei Hongshan Laboratory, Wuhan, Hubei, China, Frontiers Science Center for Animal Breeding and Sustainable Production, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China, Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Wuhan, Hubei, China

  https://orcid.org/0000-0001-5002-5351

  ⨯