Distinct prion conformers from brain and peripheral tissues of gene-targeted mice produce convergent CWD strain properties

• Joseph P. DeFranco,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Prion Research Center, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, United States of America

  https://orcid.org/0000-0003-3194-2677

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• Zoe N. Atkinson,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Visualization, Writing – review & editing

  Affiliation Prion Research Center, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, United States of America

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• Jenna Crowell,

  Roles Investigation

  Affiliation Prion Research Center, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, United States of America

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• Xutong Shi,

  Roles Investigation

  Affiliations Prion Research Center, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, United States of America, Program in Cell and Molecular Biology, Colorado State University, Fort Collins, Colorado, United States of America

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• Sehun Kim,

  Roles Investigation

  Affiliation Prion Research Center, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, United States of America

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• Julianna L. Sun,

  Roles Data curation, Investigation

  Current address – Neuronal Cell Biology Division, Department of Developmental Neurobiology, St. Jude Children’s Research Hospital, Memphis, TN, United States of America

  Affiliations Prion Research Center, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, United States of America, Program in Cell and Molecular Biology, Colorado State University, Fort Collins, Colorado, United States of America

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• Sarah J. Kane,

  Roles Conceptualization, Investigation, Writing – review & editing

  Current address – Department of Veterinary Sciences, University of Wyoming, Laramie, Wyoming, United States of America

  Affiliation Prion Research Center, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, United States of America

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• Glenn C. Telling

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

  * E-mail: glenn.telling@colostate.edu

  Affiliations Prion Research Center, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, United States of America, Program in Cell and Molecular Biology, Colorado State University, Fort Collins, Colorado, United States of America

  https://orcid.org/0000-0002-6294-1805

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