Low frequency variants can predetermine antiviral drug resistance development in herpes simplex virus type 1

• Lena Jaki,

  Roles Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

  Affiliations Faculty of Medicine, Institute of Virology, Freiburg University Medical Center, University of Freiburg, Freiburg, Germany, Section Clinical Virus Genomics, Institute of Virology, University Medical Center Freiburg, Freiburg, Germany, German Consulting Laboratory for HSV and VZV, and Medical Center— Faculty of Medicine‌‌, University of Freiburg, Freiburg, Germany

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• Florian Full,

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliation Faculty of Medicine, Institute of Virology, Freiburg University Medical Center, University of Freiburg, Freiburg, Germany

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• Udo Gieraths,

  Roles Methodology, Writing – review & editing

  Affiliations Faculty of Medicine, Institute of Virology, Freiburg University Medical Center, University of Freiburg, Freiburg, Germany, Section Clinical Virus Genomics, Institute of Virology, University Medical Center Freiburg, Freiburg, Germany

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• Valeria Falcone,

  Roles Resources, Supervision, Writing – review & editing

  Affiliations Faculty of Medicine, Institute of Virology, Freiburg University Medical Center, University of Freiburg, Freiburg, Germany, German Consulting Laboratory for HSV and VZV, and Medical Center— Faculty of Medicine‌‌, University of Freiburg, Freiburg, Germany

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• Zsolt Ruzsics,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliations Faculty of Medicine, Institute of Virology, Freiburg University Medical Center, University of Freiburg, Freiburg, Germany, German Consulting Laboratory for HSV and VZV, and Medical Center— Faculty of Medicine‌‌, University of Freiburg, Freiburg, Germany

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• Hartmut Hengel,

  Roles Conceptualization, Investigation, Writing – original draft

  Affiliations Faculty of Medicine, Institute of Virology, Freiburg University Medical Center, University of Freiburg, Freiburg, Germany, German Consulting Laboratory for HSV and VZV, and Medical Center— Faculty of Medicine‌‌, University of Freiburg, Freiburg, Germany

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• Marcus Panning,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliations Faculty of Medicine, Institute of Virology, Freiburg University Medical Center, University of Freiburg, Freiburg, Germany, Section Clinical Virus Genomics, Institute of Virology, University Medical Center Freiburg, Freiburg, Germany, German Consulting Laboratory for HSV and VZV, and Medical Center— Faculty of Medicine‌‌, University of Freiburg, Freiburg, Germany

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• Jonas Fuchs

  Roles Conceptualization, Data curation, Investigation, Supervision, Visualization, Writing – original draft

  * E-mail: jonas.fuchs@uniklinik-freiburg.de

  Affiliations Faculty of Medicine, Institute of Virology, Freiburg University Medical Center, University of Freiburg, Freiburg, Germany, Section Clinical Virus Genomics, Institute of Virology, University Medical Center Freiburg, Freiburg, Germany, German Consulting Laboratory for HSV and VZV, and Medical Center— Faculty of Medicine‌‌, University of Freiburg, Freiburg, Germany

  https://orcid.org/0000-0003-1974-212X

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