Evidence for multiple prion conformers in natural scrapie isolates

• Morikazu Imamura ,

  Contributed equally to this work with: Morikazu Imamura, Kohtaro Miyazawa

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: morikazu_imamura@med.miyazaki-u.ac.jp

  Affiliation Division of Microbiology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan

  https://orcid.org/0000-0002-7010-6228

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• Kohtaro Miyazawa ,

  Contributed equally to this work with: Morikazu Imamura, Kohtaro Miyazawa

  Roles Conceptualization, Investigation, Writing – review & editing

  Affiliation Division of Zoonosis Research, National Institute of Animal Health (NIAH), National Agriculture and Food Research Organization (NARO), Tsukuba, Ibaraki, Japan

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• Hiroyuki Okada,

  Roles Investigation, Writing – review & editing

  Current address: Food Safety Commission of Japan, Alcea Tower 13th F, Toranomon 2-2-3, Minato-ku, Tokyo 105–0001, Japan

  Affiliation Division of Infectious Animal Disease Research, National Institute of Animal Health (NIAH), National Agriculture and Food Research Organization (NARO), Tsukuba, Ibaraki, Japan

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• Minako Ohno,

  Roles Investigation, Methodology

  Affiliation Division of Microbiology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan

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• Hiromi Iguchi,

  Roles Investigation

  Affiliations Division of Biofunction Analysis, Department of Biotechnology, Frontier Science Research Center, University of Miyazaki, Miyazaki, Japan, Comprehensive Technology Center, University of Miyazaki, Miyazaki, Japan

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• Yuichi Matsuura,

  Roles Resources, Writing – review & editing

  Affiliation Division of Infectious Animal Disease Research, National Institute of Animal Health (NIAH), National Agriculture and Food Research Organization (NARO), Tsukuba, Ibaraki, Japan

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• Yoshifumi Iwamaru,

  Roles Resources, Writing – review & editing

  Affiliation Division of Infectious Animal Disease Research, National Institute of Animal Health (NIAH), National Agriculture and Food Research Organization (NARO), Tsukuba, Ibaraki, Japan

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• Hanae Takatsuki,

  Roles Writing – review & editing

  Affiliation Division of Microbiology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan

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• Tsuyoshi Mori,

  Roles Writing – review & editing

  Affiliation Division of Microbiology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan

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• Jiyan Ma,

  Roles Conceptualization, Writing – review & editing

  Affiliations Beijing Institute for Brain Research, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China, Chinese Institute for Brain Research, Beijing (CIBR), Beijing, China

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• Ryuichiro Atarashi

  Roles Funding acquisition, Supervision

  Affiliation Division of Microbiology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan

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