Fingolimod increases cellular resistance to HIV-1 infection and limits viral reservoir size in peripheral CD4⁺ T-cells

• Elisa Moraga ,

  Contributed equally to this work with: Elisa Moraga, Núria Climent

  Roles Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliations AIDS and HIV Infection Group, Fundació de Recerca Clínic Barcelona- Institut d’Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), Barcelona, Spain, Department of Medicine, Universitat de Barcelona (UB), Barcelona, Spain

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• Núria Climent ,

  Contributed equally to this work with: Elisa Moraga, Núria Climent

  Roles Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliations AIDS and HIV Infection Group, Fundació de Recerca Clínic Barcelona- Institut d’Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), Barcelona, Spain, Department of Medicine, Universitat de Barcelona (UB), Barcelona, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Infecciosas CIBER (CIBERINFEC), Instituto de Salud Carlos III (ISCIII), Madrid, Spain

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• Alejandro Sánchez-Molina,

  Roles Data curation, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations AIDS and HIV Infection Group, Fundació de Recerca Clínic Barcelona- Institut d’Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), Barcelona, Spain, Department of Medicine, Universitat de Barcelona (UB), Barcelona, Spain

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• Sònia Vicens-Artés,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation AIDS and HIV Infection Group, Fundació de Recerca Clínic Barcelona- Institut d’Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), Barcelona, Spain

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• María José Maleno,

  Roles Investigation

  Affiliation AIDS and HIV Infection Group, Fundació de Recerca Clínic Barcelona- Institut d’Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), Barcelona, Spain

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• Gabriel Valero López,

  Roles Resources

  Affiliation Neurology Department, Hospital Clínico Universitario Virgen de la Arrixaca/IMIB, CSUR Multiple Sclerosis and Clinical Neuroimmunology Unit, Murcia, Spain

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• Carlos Galera Peñaranda,

  Roles Resources

  Affiliation Hospital Clínico Universitario Virgen de la Arrixaca/ IMIB, HIV Unit, Murcia, Spain

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• Juan Ambrosioni,

  Roles Resources

  Affiliations AIDS and HIV Infection Group, Fundació de Recerca Clínic Barcelona- Institut d’Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), Barcelona, Spain, Department of Medicine, Universitat de Barcelona (UB), Barcelona, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Infecciosas CIBER (CIBERINFEC), Instituto de Salud Carlos III (ISCIII), Madrid, Spain, Infectious Diseases Service, Hospital Clínic de Barcelona, University of Barcelona, Barcelona, Spain

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• José M. Miró,

  Roles Resources, Supervision, Writing – review & editing

  Affiliations AIDS and HIV Infection Group, Fundació de Recerca Clínic Barcelona- Institut d’Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), Barcelona, Spain, Department of Medicine, Universitat de Barcelona (UB), Barcelona, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Infecciosas CIBER (CIBERINFEC), Instituto de Salud Carlos III (ISCIII), Madrid, Spain, Infectious Diseases Service, Hospital Clínic de Barcelona, University of Barcelona, Barcelona, Spain, Reial Academia de Medicina de Catalunya (RAMC), Barcelona, Spain

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• Josep Mallolas,

  Roles Resources, Supervision, Writing – review & editing

  Affiliations AIDS and HIV Infection Group, Fundació de Recerca Clínic Barcelona- Institut d’Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), Barcelona, Spain, Department of Medicine, Universitat de Barcelona (UB), Barcelona, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Infecciosas CIBER (CIBERINFEC), Instituto de Salud Carlos III (ISCIII), Madrid, Spain, Infectious Diseases Service, Hospital Clínic de Barcelona, University of Barcelona, Barcelona, Spain

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• Helena Albendín-Iglesias,

  Roles Conceptualization, Investigation, Resources, Writing – original draft, Writing – review & editing

  Affiliation Hospital Clínico Universitario Virgen de la Arrixaca/ IMIB, HIV Unit, Murcia, Spain

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• José Alcamí ,

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: ssanchez@recerca.clinic.cat (SS-P); alcami@clinic.cat (JA)

  Affiliations AIDS and HIV Infection Group, Fundació de Recerca Clínic Barcelona- Institut d’Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), Barcelona, Spain, Department of Medicine, Universitat de Barcelona (UB), Barcelona, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Infecciosas CIBER (CIBERINFEC), Instituto de Salud Carlos III (ISCIII), Madrid, Spain

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• Sonsoles Sánchez-Palomino

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: ssanchez@recerca.clinic.cat (SS-P); alcami@clinic.cat (JA)

  Affiliations AIDS and HIV Infection Group, Fundació de Recerca Clínic Barcelona- Institut d’Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), Barcelona, Spain, Department of Medicine, Universitat de Barcelona (UB), Barcelona, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Infecciosas CIBER (CIBERINFEC), Instituto de Salud Carlos III (ISCIII), Madrid, Spain

  https://orcid.org/0000-0002-9142-812X

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