An orthoflavivirus inhibitor targeting multifunctional NS2A protein, a previously unidentified target

• Doortje Borrenberghs,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Communicable diseases, Johnson & Johnson Pharmaceutical Research and Development, Beerse, Belgium

  https://orcid.org/0000-0003-1803-7509

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• Kitti Wing Ki Chan,

  Roles Investigation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Center of Global Health Discovery - Flavivirus, Program in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore

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• Sven Van Brandt,

  Roles Conceptualization, Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Janssen Research and development, Johnson & Johnson Pharmaceutical Research and Development, Beerse, Belgium

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• Steffen Jaensch,

  Roles Data curation, Formal analysis, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Janssen Research and development, Johnson & Johnson Pharmaceutical Research and Development, Beerse, Belgium

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• Milly Ming Ju Choy,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Center of Global Health Discovery - Flavivirus, Program in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore

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• Peggy Geluykens,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliation Discovery, Charles River Laboratories International Inc, Beerse, Belgium

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• Asmae El Bouayadi,

  Roles Methodology, Writing – review & editing

  Affiliation Discovery, Charles River Laboratories International Inc, Beerse, Belgium

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• Dax Lauwers,

  Roles Methodology, Writing – review & editing

  Affiliation Discovery, Charles River Laboratories International Inc, Beerse, Belgium

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• Pradeep Bist,

  Roles Methodology, Visualization, Writing – review & editing

  Affiliation Center of Global Health Discovery - Flavivirus, Program in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore

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• Bart Stoops,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Janssen Research and development, Johnson & Johnson Pharmaceutical Research and Development, Beerse, Belgium

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• Jeroen Van de Ven,

  Roles Formal analysis, Methodology, Validation, Writing – review & editing

  Affiliation Janssen Research and development, Johnson & Johnson Pharmaceutical Research and Development, Beerse, Belgium

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• Peter Vermeulen,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Janssen Research and development, Johnson & Johnson Pharmaceutical Research and Development, Beerse, Belgium

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• Sarah Megens,

  Roles Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Janssen Research and development, Johnson & Johnson Pharmaceutical Research and Development, Beerse, Belgium

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• Kim Thys,

  Roles Formal analysis, Investigation

  Affiliation Janssen Research and development, Johnson & Johnson Pharmaceutical Research and Development, Beerse, Belgium

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• Daniëlle Peeters,

  Roles Formal analysis, Methodology, Supervision, Visualization, Writing – review & editing

  Affiliation Janssen Research and development, Johnson & Johnson Pharmaceutical Research and Development, Beerse, Belgium

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• Suzanne J. F. Kaptein,

  Roles Investigation, Methodology, Validation, Writing – review & editing

  Affiliation KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Virology, Antiviral Drug & Vaccine Research Group, Leuven, Belgium

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• Johan Neyts,

  Roles Supervision, Writing – review & editing

  Affiliation KU Leuven Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Virology, Antiviral Drug & Vaccine Research Group, Leuven, Belgium

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• Subhash G. Vasudevan,

  Roles Funding acquisition, Project administration, Supervision, Writing – review & editing

  Affiliations Center of Global Health Discovery - Flavivirus, Program in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore, Institute of Biomedicine and Glycomics, Griffith University, Queensland, Australia

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• Anil Koul,

  Roles Resources, Supervision, Writing – review & editing

  Affiliation Communicable diseases, Johnson & Johnson Pharmaceutical Research and Development, Beerse, Belgium

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•  [ ... ],
• Olivia Goethals

  Roles Conceptualization, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: Ogoethal@its.jnj.com

  Affiliation Communicable diseases, Johnson & Johnson Pharmaceutical Research and Development, Beerse, Belgium

  https://orcid.org/0000-0001-8214-8989

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