HSV ICP27 hijacks host splicing factor SRSF3 to regulate pre-mRNA splicing and export for viral gene expression and immune evasion

• Shuang Tang ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: shuang.tang@fda.hhs.gov

  Affiliation Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America

  https://orcid.org/0000-0002-3084-0903

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• Amita Patel,

  Roles Data curation, Investigation, Methodology

  Affiliation Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America

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• Kazuyo Takeda,

  Roles Methodology

  Affiliation Microscopy and Imaging Core Facility, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America

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• Keith Peden,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliation Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America

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• Philip R. Krause

  Roles Conceptualization, Formal analysis, Writing – review & editing

  Affiliations Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America, Independent Consultant, Bethesda Maryland, United States of America

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