Type VI secretion system degeneration accelerates intestinal epithelial cell death in Escherichia coli O157:H7

• Zhibin Sun ,

  Contributed equally to this work with: Zhibin Sun, Chao Dong

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: zsun@njmu.edu.cn (ZS); yfyao@sjtu.edu.cn (Y-FY)

  Affiliations State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases, Nanjing Medical University, Nanjing, China, Laboratory of Bacterial Pathogenesis, Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing, China

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• Chao Dong ,

  Contributed equally to this work with: Zhibin Sun, Chao Dong

  Roles Data curation, Formal analysis, Software, Validation, Visualization, Writing – original draft

  Affiliation State Key Laboratory of Reproductive Medicine and Offspring Health, Institute of Toxicology, Nanjing Medical University, Nanjing, China

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• Pengcheng Zhou,

  Roles Investigation

  Affiliations State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases, Nanjing Medical University, Nanjing, China, Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing, China

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• Quanquan Guan,

  Roles Resources

  Affiliation State Key Laboratory of Reproductive Medicine and Offspring Health, Institute of Toxicology, Nanjing Medical University, Nanjing, China

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• Zhongli Cui,

  Roles Methodology, Writing – review & editing

  Affiliation Key Laboratory of Agricultural Environmental Microbiology, Ministry of Agriculture and Rural Affairs, College of Life Sciences of Nanjing Agricultural University, Nanjing, China

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• Yankai Xia,

  Roles Resources, Writing – review & editing

  Affiliation State Key Laboratory of Reproductive Medicine and Offspring Health, Institute of Toxicology, Nanjing Medical University, Nanjing, China

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• Yu-Feng Yao

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – review & editing

  * E-mail: zsun@njmu.edu.cn (ZS); yfyao@sjtu.edu.cn (Y-FY)

  Affiliations Laboratory of Bacterial Pathogenesis, Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Department of Infectious Diseases, Shanghai Ruijin Hospital, Shanghai, China, State Key Laboratory of Microbial Metabolism, and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China, Shanghai Key Laboratory of Emergency Prevention, Diagnosis and Treatment of Respiratory Infectious Diseases, Shanghai, China

  https://orcid.org/0000-0003-0849-3797

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