Structural and mechanistic insights into caseinolytic protease inhibition for antimicrobial development against Pseudomonas plecoglossicida

• Jingjie Chen ,

  Contributed equally to this work with: Jingjie Chen, Ping Zhang, Hongxin Guan

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Writing – original draft

  Affiliations National Key Laboratory of Agricultural Microbiology, Hubei Hongshan Laboratory, Engineering Research Center of Green Development for Conventional Aquatic Biological Industry in the Yangtze River Economic Belt, Ministry of Education, College of Fisheries, Huazhong Agricultural University, Wuhan, China, Key Laboratory of Marine Biotechnology of Fujian Province, College of Marine Sciences, Fujian Agriculture and Forestry University, Fuzhou, China

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• Ping Zhang ,

  Contributed equally to this work with: Jingjie Chen, Ping Zhang, Hongxin Guan

  Roles Formal analysis, Investigation

  Affiliation Key Laboratory of Microbial Pathogenesis and Interventions of Fujian Province University, College of Life Sciences, Fujian Normal University, Fuzhou, China

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• Hongxin Guan ,

  Contributed equally to this work with: Jingjie Chen, Ping Zhang, Hongxin Guan

  Roles Formal analysis, Investigation

  Affiliation Key Laboratory of Microbial Pathogenesis and Interventions of Fujian Province University, College of Life Sciences, Fujian Normal University, Fuzhou, China

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• Bing Gong,

  Roles Data curation, Investigation

  Affiliation Key Laboratory of Marine Biotechnology of Fujian Province, College of Marine Sciences, Fujian Agriculture and Forestry University, Fuzhou, China

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• Xiaoding Li,

  Roles Data curation, Investigation

  Affiliation Key Laboratory of Microbial Pathogenesis and Interventions of Fujian Province University, College of Life Sciences, Fujian Normal University, Fuzhou, China

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• Zekai Li,

  Roles Data curation, Software

  Affiliation Key Laboratory of Microbial Pathogenesis and Interventions of Fujian Province University, College of Life Sciences, Fujian Normal University, Fuzhou, China

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• Fan Li,

  Roles Data curation, Software

  Affiliation Key Laboratory of Microbial Pathogenesis and Interventions of Fujian Province University, College of Life Sciences, Fujian Normal University, Fuzhou, China

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• Biao Zhou,

  Roles Data curation, Software

  Affiliation Guangzhou Institutes of Biomedicine and Health Chinese Academy of Sciences, Guangzhou, China

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• Xuemin Chen ,

  Roles Data curation, Methodology, Software

  * E-mail: cxmsherman@163.com (XMC); chenxinhua@tio.org.cn (XHC); ouyangsy@fjnu.edu.cn (SO); yonganzhang@mail.hzau.edu.cn (Y-AZ)

  Affiliation School of Life Sciences, Anhui University, Hefei, China

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• Xinhua Chen ,

  Roles Formal analysis, Funding acquisition, Writing – review & editing

  * E-mail: cxmsherman@163.com (XMC); chenxinhua@tio.org.cn (XHC); ouyangsy@fjnu.edu.cn (SO); yonganzhang@mail.hzau.edu.cn (Y-AZ)

  Affiliation Key Laboratory of Marine Biotechnology of Fujian Province, College of Marine Sciences, Fujian Agriculture and Forestry University, Fuzhou, China

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• Songying Ouyang ,

  Roles Formal analysis, Funding acquisition

  * E-mail: cxmsherman@163.com (XMC); chenxinhua@tio.org.cn (XHC); ouyangsy@fjnu.edu.cn (SO); yonganzhang@mail.hzau.edu.cn (Y-AZ)

  Affiliation Key Laboratory of Microbial Pathogenesis and Interventions of Fujian Province University, College of Life Sciences, Fujian Normal University, Fuzhou, China

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• Yong-An Zhang

  Roles Funding acquisition, Supervision, Writing – review & editing

  * E-mail: cxmsherman@163.com (XMC); chenxinhua@tio.org.cn (XHC); ouyangsy@fjnu.edu.cn (SO); yonganzhang@mail.hzau.edu.cn (Y-AZ)

  Affiliation National Key Laboratory of Agricultural Microbiology, Hubei Hongshan Laboratory, Engineering Research Center of Green Development for Conventional Aquatic Biological Industry in the Yangtze River Economic Belt, Ministry of Education, College of Fisheries, Huazhong Agricultural University, Wuhan, China

  https://orcid.org/0000-0002-9956-3879

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