Intra-patient neuraminidase mutations in avian H5N1 influenza virus reduce sialidase activity to complement weaker hemagglutinin binding and facilitate human infection

• Yohei Watanabe ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: nabe@koto.kpu-m.ac.jp

  Affiliations Department of Virology, The JIKEI University School of Medicine, Tokyo, Japan, Department of Infectious Diseases, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan

  https://orcid.org/0000-0002-8305-6952

  ⨯
• Madiha S. Ibrahim,

  Roles Investigation, Resources

  Affiliation Department of Virology, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt

  ⨯
• Yasuha Arai,

  Roles Investigation, Validation

  Affiliation Department of Infectious Diseases, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan

  ⨯
• Daisuke Kuroda,

  Roles Formal analysis, Writing – review & editing

  Affiliation Department of Biosciences, College of Humanities and Sciences, Nihon University, Tokyo, Japan

  ⨯
• Emad M. Elgendy,

  Roles Resources, Writing – review & editing

  Affiliation Department of Virology, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt

  ⨯
• Shin-ichi Nakakita,

  Roles Methodology, Writing – review & editing

  Affiliation Division of Functional Glycomics, Kagawa University, Kagawa, Japan

  ⨯
• Yohei Takeda,

  Roles Writing – review & editing

  Affiliations Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan, Research Center for Global Agromedicine, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan

  ⨯
• Vuong Nghia Bui,

  Roles Writing – review & editing

  Affiliation Virology Department, National Institute of Veterinary Research, Hanoi, Vietnam

  ⨯
• Takao Ono,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Mechanical Science and Bioengineering, Graduate School of Engineering Science, The University of Osaka, Osaka, Japan

  ⨯
• Shota Ushiba,

  Roles Writing – review & editing

  Affiliation Murata Manufacturing Co., Ltd, Kyoto, Japan

  ⨯
• Tomo Daidoji,

  Roles Methodology, Resources, Validation, Funding acquisition, Writing – review & editing

  Affiliations Department of Infectious Diseases, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan, Department of Pathobiology, School of Veterinary Medicine, Rakuno Gakuen University, Hokkaido, Japan

  ⨯
• Nongluk Sriwilaijaroen,

  Roles Methodology, Resources, Writing – review & editing

  Affiliations Department of Preclinical Sciences, Faculty of Medicine, Thammasat University, Pathumthani, Thailand, Department of Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Japan

  ⨯
• Haruko Ogawa,

  Roles Writing – review & editing

  Affiliation Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan

  ⨯
• Kazuhiko Matsumoto,

  Roles Funding acquisition, Writing – review & editing

  Affiliation SANKEN, The University of Osaka, Osaka, Japan

  ⨯
• Yasuo Suzuki,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Department of Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Japan

  ⨯
•  [ ... ],
• Takaaki Nakaya

  Roles Validation, Writing – review & editing

  Affiliation Department of Infectious Diseases, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan

  ⨯
• [ view all ]
• [ view less ]