Excessive C5 conversion prevents C9 polymerisation and subsequent MAC-dependent killing of Klebsiella pneumoniae

• Kulsum M. Dawoodbhoy,

  Roles Conceptualization, Formal analysis, Investigation, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands

  https://orcid.org/0000-0002-8356-2273

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• Coco R. Beudeker,

  Roles Conceptualization, Writing – review & editing

  Affiliations Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands, Wilhemina Children’s Hospital, Pediatric Infectious Diseases and Immunology, University Medical Centre Utrecht, Utrecht, The Netherlands

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• Panagiotis Theofilidis,

  Roles Investigation

  Affiliation Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands

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• Frerich M. Masson,

  Roles Investigation

  Affiliation Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands

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• Michiel van der Flier,

  Roles Funding acquisition, Writing – review & editing

  Affiliations Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands, Wilhemina Children’s Hospital, Pediatric Infectious Diseases and Immunology, University Medical Centre Utrecht, Utrecht, The Netherlands

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• Suzan H. M. Rooijakkers,

  Roles Funding acquisition, Writing – review & editing

  Affiliation Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands

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• Bart W. Bardoel ,

  Roles Conceptualization, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: b.w.bardoel-2@umcutrecht.nl

  Affiliation Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands

  https://orcid.org/0000-0001-6450-277X

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• Dennis J. Doorduijn

  Roles Conceptualization, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands

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