The receptor binding properties of H5Ny influenza A viruses have evolved to bind to avian-type mucin-like O-glycans

• Julia Weber,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg Utrecht, Utrecht, The Netherlands, Institute of Applied Synthetic Chemistry, Vienna University of Technology, Vienna, Austria

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• Niels L. D. Ponse,

  Roles Investigation, Validation, Writing – review & editing

  Affiliation Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg Utrecht, Utrecht, The Netherlands

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• Xueyong Zhu,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America

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• María Ríos Carrasco,

  Roles Formal analysis, Investigation, Validation, Visualization, Writing – review & editing

  Affiliation Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg Utrecht, Utrecht, The Netherlands

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• Alvin X. Han,

  Roles Formal analysis, Investigation, Validation, Writing – review & editing

  Affiliation Department of Medical Microbiology & Infection Prevention, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands

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• Mathis Funk,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Validation, Visualization

  Affiliation Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands

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• Ting-Hui Lin,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation

  Affiliation Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America

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• Alba Gabarroca García,

  Roles Formal analysis, Investigation, Validation, Visualization, Writing – review & editing

  Affiliation Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg Utrecht, Utrecht, The Netherlands

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• Cindy M. Spruit,

  Roles Formal analysis, Validation, Writing – review & editing

  Affiliation Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg Utrecht, Utrecht, The Netherlands

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• Ding Zhang,

  Roles Formal analysis, Investigation, Validation, Writing – review & editing

  Affiliation Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America

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• Wenli Yu,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America

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• Ian A. Wilson,

  Roles Conceptualization, Funding acquisition, Resources, Writing – review & editing

  Affiliations Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America, Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America

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• Mathilde Richard,

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliation Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands

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• Geert-Jan Boons ,

  Roles Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: r.vries@uu.nl (RPdV); g.j.p.h.boons@uu.nl (G-JB)

  Affiliations Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg Utrecht, Utrecht, The Netherlands, Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, United States of America

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• Robert P. de Vries

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: r.vries@uu.nl (RPdV); g.j.p.h.boons@uu.nl (G-JB)

  Affiliation Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg Utrecht, Utrecht, The Netherlands

  https://orcid.org/0000-0002-1586-4464

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