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Open Access
Peer-reviewed
Research Article
Inhibition of Wnt signaling in primary human hepatocytes promotes Plasmodium falciparum liver stage development
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Abhishek Kanyal ,
Contributed equally to this work with: Abhishek Kanyal, Geert-Jan van Gemert, Haoyu Wu, Richárd Bártfai, Annie S. P. Yang
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Science, Radboud University, Nijmegen, The Netherlands
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Geert-Jan van Gemert ,
Contributed equally to this work with: Abhishek Kanyal, Geert-Jan van Gemert, Haoyu Wu, Richárd Bártfai, Annie S. P. Yang
Roles Data curation, Writing – review & editing
Affiliation Radboud Center of Infectious Diseases, Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands
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Haoyu Wu ,
Contributed equally to this work with: Abhishek Kanyal, Geert-Jan van Gemert, Haoyu Wu, Richárd Bártfai, Annie S. P. Yang
Roles Conceptualization, Data curation, Writing – review & editing
Affiliations Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Science, Radboud University, Nijmegen, The Netherlands, CAS Key Laboratory of Regenerative Biology, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
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Alex van der Starre,
Roles Data curation, Investigation, Methodology
Affiliation Radboud Center of Infectious Diseases, Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands
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Johannes H.W. de Wilt,
Roles Data curation, Writing – review & editing
Affiliation Department of Surgery, Radboud University Medical Center, Nijmegen, The Netherlands
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Teun Bousema,
Roles Writing – review & editing
Affiliation Radboud Center of Infectious Diseases, Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands
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Robert W. Sauerwein,
Roles Conceptualization, Writing – original draft, Writing – review & editing
Affiliation Radboud Center of Infectious Diseases, Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands
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Richárd Bártfai ,
Contributed equally to this work with: Abhishek Kanyal, Geert-Jan van Gemert, Haoyu Wu, Richárd Bártfai, Annie S. P. Yang
Roles Conceptualization, Funding acquisition, Writing – original draft, Writing – review & editing
* E-mail: r.bartfai@science.ru.nl (RB); a.s.yang@lumc.nl (ASPY)
Affiliation Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Science, Radboud University, Nijmegen, The Netherlands
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Annie S. P. Yang
Contributed equally to this work with: Abhishek Kanyal, Geert-Jan van Gemert, Haoyu Wu, Richárd Bártfai, Annie S. P. Yang
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Writing – original draft, Writing – review & editing
* E-mail: r.bartfai@science.ru.nl (RB); a.s.yang@lumc.nl (ASPY)
Current address: Leiden University Center for Infectious Diseases (LUCID), Leiden University Medical Center, Leiden, the Netherlands
Affiliation Radboud Center of Infectious Diseases, Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands
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Inhibition of Wnt signaling in primary human hepatocytes promotes Plasmodium falciparum liver stage development
- Abhishek Kanyal,
- Geert-Jan van Gemert,
- Haoyu Wu,
- Alex van der Starre,
- Johannes H.W. de Wilt,
- Teun Bousema,
- Robert W. Sauerwein,
- Richárd Bártfai,
- Annie S. P. Yang
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- Published: December 22, 2025
- https://doi.org/10.1371/journal.ppat.1013800