High prevalence and emerging positive association of kelch13 R622I and HRP2-based RDT negativity in Plasmodium falciparum in northern Ethiopia

• Ayalew Jejaw Zeleke ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: ayalewjejaw@gmail.com (AJZ); jeffrey_bailey@brown.edu (JAB)

  Affiliation Department of Medical Parasitology, School of Biomedical and Laboratory Sciences, University of Gondar, Gondar, Ethiopia

  https://orcid.org/0000-0002-9640-4784

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• Abebe A. Fola,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island, United States of America, Center for Computational Molecular Biology, Brown University, Providence, Rhode Island, United States of America

  ⨯
• George A. Tollefson,

  Roles Data curation, Formal analysis, Software, Visualization

  Affiliations Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island, United States of America, Center for Computational Molecular Biology, Brown University, Providence, Rhode Island, United States of America

  ⨯
• Karamako Niaré,

  Roles Visualization

  Affiliations Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island, United States of America, Center for Computational Molecular Biology, Brown University, Providence, Rhode Island, United States of America

  ⨯
• Alec Leonetti,

  Roles Investigation

  Affiliation Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island, United States of America

  ⨯
• Om Taropawala,

  Roles Investigation

  Affiliations Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island, United States of America, School of Public Health, Brown University, Providence, Rhode Island, United States of America

  ⨯
• Jacob Marglous,

  Roles Visualization

  Affiliations Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island, United States of America, Center for Computational Molecular Biology, Brown University, Providence, Rhode Island, United States of America

  ⨯
• Rebecca Crudale,

  Roles Investigation

  Affiliation Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island, United States of America

  ⨯
• Bokretsion G. Brhane,

  Roles Investigation, Methodology

  Affiliations Ethiopian Public Health Institute, Addis Ababa, Ethiopia, Department of Microbial, Cellular and Molecular Biology, Addis Ababa University, Addis Ababa, Ethiopia

  ⨯
• Ashenafi Assefa,

  Roles Investigation, Methodology

  Affiliations Ethiopian Public Health Institute, Addis Ababa, Ethiopia, Institute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

  ⨯
• Patience Kiyuka,

  Roles Supervision

  Affiliations Kenya Medical Research Institute, Center for Geographic Medicine Research Coast, Kilifi, Kenya, KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya

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• Jonathan B. Parr,

  Roles Methodology, Writing – review & editing

  Affiliations Institute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

  ⨯
• Asrat Hailu,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliations Department of Medical Parasitology, School of Biomedical and Laboratory Sciences, University of Gondar, Gondar, Ethiopia, Department of Microbiology, Immunology and Parasitology, Faculty of Medicine, Addis Ababa University, Addis Ababa, Ethiopia

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• Mulugeta Aemero Tegegne ,

  Roles Conceptualization, Supervision, Writing – review & editing

  ¶‡ These authors are co-senior authors on this work.

  Affiliation Department of Medical Parasitology, School of Biomedical and Laboratory Sciences, University of Gondar, Gondar, Ethiopia

  ⨯
• Jeffrey A. Bailey

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Resources, Supervision, Validation, Visualization, Writing – review & editing

  * E-mail: ayalewjejaw@gmail.com (AJZ); jeffrey_bailey@brown.edu (JAB)

  ¶‡ These authors are co-senior authors on this work.

  Affiliations Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island, United States of America, Center for Computational Molecular Biology, Brown University, Providence, Rhode Island, United States of America

  https://orcid.org/0000-0002-6899-8204

  ⨯