Genome-wide CRISPR screen reveals PEX11B as a host restriction factor against ORFV through membrane fluidity regulation

• Xiaoran Gao ,

  Contributed equally to this work with: Xiaoran Gao, Jinyang Hao

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot, P.R.China

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• Jinyang Hao ,

  Contributed equally to this work with: Xiaoran Gao, Jinyang Hao

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliation The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot, P.R.China

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• Sha Lu,

  Roles Conceptualization, Data curation, Methodology

  Affiliations The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot, P.R.China, College of Basic Medical Sciences, Inner Mongolia Medical University, Hohhot, P.R. China

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• Shida Wang,

  Roles Data curation, Validation

  Affiliation The State Key Laboratory for Animal Disease Control, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, P.R. China

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• Yu Sun,

  Roles Investigation, Validation

  Affiliation The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot, P.R.China

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• Xin Ke,

  Roles Validation

  Affiliation The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot, P.R.China

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• Xia Gao,

  Roles Validation

  Affiliation The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot, P.R.China

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• Yuan Su,

  Roles Validation

  Affiliation The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot, P.R.China

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• Yuze Sun,

  Roles Investigation

  Affiliation The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot, P.R.China

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• Yu Tian,

  Roles Validation

  Affiliation The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot, P.R.China

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• Wenyu Yan,

  Roles Validation

  Affiliation The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot, P.R.China

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• Jinliang Wang,

  Roles Conceptualization, Supervision

  Affiliation The State Key Laboratory for Animal Disease Control, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, P.R. China

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• Zhong Zheng,

  Roles Data curation, Resources

  Affiliation The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot, P.R.China

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• Rong Hai,

  Roles Methodology, Supervision

  Affiliation Department of Microbiology and Plant Pathology, University of California, Riverside, California, United States of America

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• Qianyi Zhang,

  Roles Resources

  Affiliation China Institute of Veterinary Drug Control, Beijing, P.R. China

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• Jingfei Wang,

  Roles Methodology

  Affiliation The State Key Laboratory for Animal Disease Control, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, P.R. China

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• Wei Hu ,

  Roles Funding acquisition, Resources, Writing – review & editing

  * E-mail: huw@imu.edu.cn (WH); guojun.wang@imu.edu.cnfig (GW)

  Affiliation The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot, P.R.China

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•  [ ... ],
• Guojun Wang

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: huw@imu.edu.cn (WH); guojun.wang@imu.edu.cnfig (GW)

  ¶‡ Lead contact.

  Affiliation The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University, Hohhot, P.R.China

  https://orcid.org/0000-0002-8578-6844

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