The recombinant zoster vaccine induces trained immunity in monocytes through persistent downregulation of TGFβ

• Michael J. Johnson,

  Roles Data curation, Formal analysis, Project administration, Writing – original draft, Writing – review & editing

  Affiliation Department of Pediatrics, University of Colorado School of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America

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• Megan Crotteau,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Pediatrics, University of Colorado School of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America

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• Debashis Ghosh,

  Roles Supervision, Writing – review & editing

  Affiliation Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America

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• Thao Vu,

  Roles Formal analysis, Writing – review & editing

  Affiliation Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America

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• Luke Trinity,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, United States of America

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• Radu Marches,

  Roles Data curation, Writing – review & editing

  Affiliation The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, United States of America

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• Duygu Ucar,

  Roles Supervision, Writing – review & editing

  Affiliation The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, United States of America

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• Myron J. Levin,

  Roles Funding acquisition, Writing – review & editing

  Affiliations Department of Pediatrics, University of Colorado School of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America, Department of Medicine, University of Colorado School of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America

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• Adriana Weinberg

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: Adriana.Weinberg@cuanschutz.edu

  Affiliations Department of Pediatrics, University of Colorado School of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America, Department of Medicine, University of Colorado School of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America, Department of Pathology, University of School of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America

  https://orcid.org/0000-0001-6920-0623

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