The cervicovaginal microbiome associates with spatially restricted host transcriptional signatures throughout the human ectocervical epithelium and submucosa

• Vilde Kaldhusdal ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: vilde.kaldhusdal@ki.se

  Affiliations Department of Medicine Solna, Division of Infectious Diseases, Karolinska Institutet, Stockholm, Sweden, Department of Infectious Diseases, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden

  https://orcid.org/0000-0002-2485-5156

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• Mathias Franzén Boger,

  Roles Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliations Department of Medicine Solna, Division of Infectious Diseases, Karolinska Institutet, Stockholm, Sweden, Department of Infectious Diseases, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden

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• Adam D. Burgener,

  Roles Funding acquisition, Investigation, Methodology, Supervision, Writing – review & editing

  Affiliations Department of Medicine Solna, Division of Infectious Diseases, Karolinska Institutet, Stockholm, Sweden, Department of Infectious Diseases, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden, Center for Global Health and Diseases, Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America, Department of Obstetrics, Gynecology and Reproductive Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, Canada

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• Julie Lajoie,

  Roles Data curation, Investigation, Methodology, Validation, Writing – review & editing

  Affiliations Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada, Department of Medical Microbiology and Immunology, University of Nairobi, Nairobi, Kenya

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• Kenneth Omollo,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliations Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada, Partners for Health and Development in Africa, Nairobi, Kenya

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• Joshua Kimani,

  Roles Conceptualization, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliations Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada, Partners for Health and Development in Africa, Nairobi, Kenya

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• Annelie Tjernlund,

  Roles Investigation, Methodology, Supervision, Writing – review & editing

  Affiliations Department of Medicine Solna, Division of Infectious Diseases, Karolinska Institutet, Stockholm, Sweden, Department of Infectious Diseases, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden

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• Keith R. Fowke,

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  Affiliations Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Canada, Department of Medical Microbiology and Immunology, University of Nairobi, Nairobi, Kenya, Partners for Health and Development in Africa, Nairobi, Kenya, Department of Community Health Sciences, University of Manitoba, Winnipeg, Canada

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• Douglas S. Kwon,

  Roles Conceptualization, Project administration, Resources, Supervision, Validation, Writing – review & editing

  Affiliation Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America

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• Gabriella Edfeldt,

  Roles Data curation, Investigation, Methodology, Software, Validation, Writing – review & editing

  Affiliations Department of Medicine Solna, Division of Infectious Diseases, Karolinska Institutet, Stockholm, Sweden, Department of Infectious Diseases, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden

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• Kristina Broliden

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliations Department of Medicine Solna, Division of Infectious Diseases, Karolinska Institutet, Stockholm, Sweden, Department of Infectious Diseases, Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden

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