Discovery of a potent anti-Zika virus benzamide series targeting the viral protein NS4B

• Donghoon Chung ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: hoon.chung@louisville.edu (DC); t.bannister@ufl.edu (TDB)

  Affiliation Center for Predictive Medicine, Department of Microbiology Immunology, School of Medicine, University of Louisville, Louisville, Kentucky, United States of America

  https://orcid.org/0000-0003-2626-172X

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• Yuka Otsuka,

  Roles Investigation, Methodology

  Affiliation Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida, United States of America

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• Eunjung Kim,

  Roles Investigation

  Affiliation Center for Predictive Medicine, Department of Microbiology Immunology, School of Medicine, University of Louisville, Louisville, Kentucky, United States of America

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• Sultan Ullah,

  Roles Investigation

  Affiliation Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida, United States of America

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• Nicole M. Kennedy,

  Roles Investigation

  Affiliation Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida, United States of America

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• Khac Huy Ngo,

  Roles Investigation

  Affiliation Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore

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• Jinjoo Kang,

  Roles Investigation, Methodology

  Affiliation Center for Predictive Medicine, Department of Microbiology Immunology, School of Medicine, University of Louisville, Louisville, Kentucky, United States of America

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• Reece Tomlinson,

  Roles Investigation

  Affiliation Center for Predictive Medicine, Department of Microbiology Immunology, School of Medicine, University of Louisville, Louisville, Kentucky, United States of America

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• Brian Alejandro,

  Roles Investigation

  Affiliation Center for Predictive Medicine, Department of Microbiology Immunology, School of Medicine, University of Louisville, Louisville, Kentucky, United States of America

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• Koji Barnaby,

  Roles Investigation, Writing – review & editing

  Affiliation Center for Predictive Medicine, Department of Microbiology Immunology, School of Medicine, University of Louisville, Louisville, Kentucky, United States of America

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• Jeffrey Miller,

  Roles Investigation, Writing – review & editing

  Affiliation Center for Predictive Medicine, Department of Microbiology Immunology, School of Medicine, University of Louisville, Louisville, Kentucky, United States of America

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• Justin Shumate,

  Roles Investigation

  Affiliation Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida, United States of America

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• Chwee Fang Teo,

  Roles Investigation

  Affiliation Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore

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• Yaw Bia Tan,

  Roles Investigation

  Affiliation Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore

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• Che Shin Chew,

  Roles Investigation

  Affiliation Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore

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• CongBao Kang,

  Roles Investigation, Methodology

  Affiliation Experimental Drug Development Centre, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore

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• Dahai Luo,

  Roles Project administration, Writing – original draft, Writing – review & editing

  Affiliations Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore, National Centre for Infectious Diseases, Singapore, Singapore, Institute of Structural Biology, Nanyang Technological University, Singapore, Singapore

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• Louis Scampavia,

  Roles Conceptualization, Data curation, Funding acquisition, Project administration, Supervision, Writing – review & editing

  Affiliation Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida, United States of America

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• Timothy P. Spicer,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida, United States of America

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•  [ ... ],
• Thomas D. Bannister

  Roles Conceptualization, Data curation, Funding acquisition, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: hoon.chung@louisville.edu (DC); t.bannister@ufl.edu (TDB)

  Affiliation Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, Florida, United States of America

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