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Monitoring intracellular replication dynamics unveils high proportion of non-replicating antibiotic-tolerant Staphylococcus aureus inside osteoblasts
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Florian C. Marro,
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliations Evotec ID Lyon, In Vitro Biology, Infectious Diseases and Antibacterials Unit, Lyon, France, Centre International de Recherche en Infectiologie (CIRI), Inserm U1111, Université Claude Bernard Lyon 1, CNRS UMR5308, ENS Lyon, Lyon, France
⨯ - Jacques Brocard,
- Allison Faure,
- Angélique Sion,
- Paul O. Verhoeven,
- Laurie Canonne-Desbiolles,
- Laurence Conraux,
- Laura Jaffrelot,
- Chantal Monlong,
- Ariel J. Blocker,
- Nelly Dubarry,
- Frédéric Laurent,
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Jérôme Josse
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: jerome.josse@univ-lyon1.fr
Affiliation Centre International de Recherche en Infectiologie (CIRI), Inserm U1111, Université Claude Bernard Lyon 1, CNRS UMR5308, ENS Lyon, Lyon, France
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https://orcid.org/0009-0005-1470-5460
Monitoring intracellular replication dynamics unveils high proportion of non-replicating antibiotic-tolerant Staphylococcus aureus inside osteoblasts
- Florian C. Marro,
- Jacques Brocard,
- Allison Faure,
- Angélique Sion,
- Paul O. Verhoeven,
- Laurie Canonne-Desbiolles,
- Laurence Conraux,
- Laura Jaffrelot,
- Chantal Monlong,
- Ariel J. Blocker
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- Published: September 23, 2025
- https://doi.org/10.1371/journal.ppat.1013525