The interaction between GCN2 and eIF2 mediates the resistance of cotton bollworm to the Bacillus thuringiensis Cry1Ac toxin

Caihong Zhang; Jizhen Wei; Ningning Li; Zaw Lin Naing; Ei Thinzar Soe; Jinrong Tang; Huan Yu; Fengyun Fang; Gemei Liang

doi:10.1371/journal.ppat.1013510

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Open Access

Peer-reviewed

Research Article

The interaction between GCN2 and eIF2 mediates the resistance of cotton bollworm to the Bacillus thuringiensis Cry1Ac toxin

Caihong Zhang,

Roles Data curation, Investigation, Writing – original draft

Affiliation State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, PR China
⨯
Jizhen Wei ,

Roles Funding acquisition, Resources, Supervision, Writing – original draft, Writing – review & editing

* E-mail: weijizhen1986@163.com (JW); gmliang@ippcaas.cn (GL)

Affiliation State Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping/College of Plant Protection, Henan Agricultural University, Zhengzhou, China

https://orcid.org/0000-0001-6487-4725

⨯
Ningning Li,

Roles Investigation, Visualization

Affiliation State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, PR China
⨯
Zaw Lin Naing,

Roles Investigation, Validation

Affiliation State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, PR China
⨯
Ei Thinzar Soe,

Roles Data curation, Investigation

Affiliation State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, PR China
⨯
Jinrong Tang,

Roles Investigation, Visualization

Affiliation State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, PR China
⨯
Huan Yu,

Roles Data curation, Investigation

Affiliation State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, PR China
⨯
Fengyun Fang,

Roles Investigation, Validation

Affiliation State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, PR China
⨯
Gemei Liang

Roles Funding acquisition, Resources, Supervision, Writing – original draft, Writing – review & editing

* E-mail: weijizhen1986@163.com (JW); gmliang@ippcaas.cn (GL)

Affiliation State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, PR China
⨯

The interaction between GCN2 and eIF2 mediates the resistance of cotton bollworm to the Bacillus thuringiensis Cry1Ac toxin

Caihong Zhang,
Jizhen Wei,
Ningning Li,
Zaw Lin Naing,
Ei Thinzar Soe,
Jinrong Tang,
Huan Yu,
Fengyun Fang,
Gemei Liang

Published: September 15, 2025
https://doi.org/10.1371/journal.ppat.1013510

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