The multifaceted role of the viral 2A protease in enterovirus replication and antagonism of host antiviral responses

• Jelle G. Schipper ,

  Contributed equally to this work with: Jelle G. Schipper, Chiara Aloise

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Section of Virology, Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands

  ⨯
• Chiara Aloise ,

  Contributed equally to this work with: Jelle G. Schipper, Chiara Aloise

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Section of Virology, Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands

  ⨯
• Sereina O. Sutter,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Section of Virology, Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands

  ⨯
• Marleen Zwaagstra,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Section of Virology, Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands

  ⨯
• Arno L.W. van Vliet,

  Roles Investigation, Writing – review & editing

  Affiliation Section of Virology, Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands

  ⨯
• Rana Abdelnabi,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliations Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology, Antiviral Drug & Vaccine Research Group, KU Leuven, Leuven, Belgium, KU Leuven - Department of Microbiology, Immunology and Transplantation, VirusBank Platform, Leuven, Belgium

  ⨯
• Bob Ignacio,

  Roles Resources, Writing – review & editing

  Affiliation Department of Synthetic Organic Chemistry, Chemical Biology Lab, Radboud University, Nijmegen, the Netherlands

  ⨯
• Kimberly M. Bonger,

  Roles Resources, Writing – review & editing

  Current address: Department of Chemical Biology & Immunology, Leiden Institute of Chemistry, Leiden University, Leiden, the Netherlands

  Affiliation Department of Synthetic Organic Chemistry, Chemical Biology Lab, Radboud University, Nijmegen, the Netherlands

  ⨯
• Dagmar Roelofs,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Division of Pathology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands

  ⨯
• Judith M.A. van den Brand,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Division of Pathology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands

  ⨯
• Richard W. Wubbolts,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Center for Cell Imaging, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands

  ⨯
• Lucas J.M. Bruurs,

  Roles Methodology, Resources, Writing – review & editing

  Current address: Bilthoven Biologicals B.V., Antonie van Leeuwenhoeklaan 9, AL Bilthoven, The Netherlands

  Affiliation Oncode Institute, Hubrecht Institute–KNAW and University Medical Center Utrecht, Utrecht, the Netherlands

  ⨯
• Hendrik Jan Thibaut,

  Roles Methodology, Supervision, Writing – review & editing

  Affiliation Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology, Antiviral Drug & Vaccine Research Group, KU Leuven, Leuven, Belgium

  ⨯
• Johan Neyts,

  Roles Funding acquisition, Methodology, Supervision, Writing – review & editing

  Affiliations Department of Microbiology, Immunology and Transplantation, Rega Institute, Virology, Antiviral Drug & Vaccine Research Group, KU Leuven, Leuven, Belgium, KU Leuven - Department of Microbiology, Immunology and Transplantation, VirusBank Platform, Leuven, Belgium

  ⨯
• Marvin E. Tanenbaum ,

  Roles Data curation, Funding acquisition, Methodology, Project administration, Supervision, Writing – review & editing

  * E-mail: f.j.m.vankuppeveld@uu.nl (FJMvK); m.tanenbaum@hubrecht.eu (MET)

  ¶‡ These authors share senior authorship.

  Affiliations Oncode Institute, Hubrecht Institute–KNAW and University Medical Center Utrecht, Utrecht, the Netherlands, Department of Bionanoscience, Delft University of Technology, Delft, the Netherlands

  ⨯
•  [ ... ],
• Frank J. M. van Kuppeveld

  Roles Conceptualization, Data curation, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: f.j.m.vankuppeveld@uu.nl (FJMvK); m.tanenbaum@hubrecht.eu (MET)

  ¶‡ These authors share senior authorship.

  Affiliation Section of Virology, Division of Infectious Diseases and Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands

  https://orcid.org/0000-0001-5800-749X

  ⨯
• [ view all ]
• [ view less ]